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from the gut/brain connection

Lipopolysaccharide (LPS) from gram-negative bacteria translocates into systemic circulation, triggering NF-B signalling and a cytokine storm (TNF-, IL-1, IL-6, IL-8)

However, MS therapy has been enriched with a variety of therapeutic approaches to modify the disease course, progression, and control of symptoms (Polman et al., 2006

Visible results require patience - first subtle improvements appear at 4-6 weeks, noticeable anti-aging effects at 6-12 weeks, and maximum benefits at 12-24 weeks with diminishing returns thereafter

doi: 10.1371/journal.pone.0079466

Target genes used in the mouse model were CAT (NM_009804.2), GSH-Px (NM_001329527.1), SOD1 (NM_011434.2), and GAPDH (NM_001289726.2)