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Additionally, inhibition of CD38 in the AD mouse model restored NAD + levels, decreased mitochondrial ROS production and plaque depositions in the hippocampus and cortex, and improved cognitive abilities 158

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Oncogene 4(11):1363-74, 1989

657 Importantly, intraventricular injection of Fer-1 significantly decreases iron deposition and neuronal degeneration, improving motor and cognitive function