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The extended-release formulation exenatide once-weekly (Bydureon) can be given at any time of day, with or without meals, on the same day each week

While there were reductions in cardiovascular death (12%) and all-cause mortality (14%), the rates of fatal myocardial infarction (MI) and hospitalization for MI were not significantly different (80)

Gerstein HC, Sattar N, Rosenstock J et al (2021) Cardiovascular and renal outcomes with efpeglenatide in type 2 diabetes

We demonstrated that GLP-1 enhances physical endurance by inducing skeletal muscle remodeling, which may be mediated by GLP-1R/AMPK signaling

Federal Drug Administration have received reports of adverse events, some including hospitalizations on compounded GLP-1 drugs due to dosing errors or incorrect doses with self-administration

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