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Proc Jpn Acad (1987) 63:2313.10.2183/pjab.63.231 110 DanforsTvon KnorringALHartvigPLangstromBMoulderRStrombergBet alTetrahydrobiopterin in the treatment of children with autistic disorder: a double-blind placebo-controlled crossover study

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It leads to reduced T cell proliferation and diminished cytokine production such as IL-2 and IFN- [307, 308], a condition seen in aged individuals as well [309, 310], resulting in an increased susceptibility to infections

In addition, melatonin appears to hinder the activation, degranulation and infiltration of mast cells, which are involved in skin damage (99)