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[12] Postulated effects of glutathione on pigmentation The role of glutathione as a skin-lightening agent was an accidental discovery when skin lightening was noticed as a side effect of large doses of glutathione

Herein, we successfully switched a patient with acromegaly from a DPP-4 inhibitor to a GLP-1 analog due to pasireotide-induced deterioration of glycemic control

A bulk drug substance is an active pharmaceutical ingredient intended to be incorporated into a finished drug product and to provide pharmacological activity or another direct effect

The molecule was developed by Frank Ng's group at Monash University and Metabolic Pharmaceuticals in Australia during the 1990s and 2000s as a potential anti-obesity drug intended to isolate the lipolytic region of hGH without activating the growth hormone receptor or raising IGF-1.nnIn published preclinical work, the fragment has been shown to stimulate lipolysis, suppress lipogenesis, and modulate the beta-3 adrenergic receptor pathway in adipose tissue rather than acting through the classical hGH receptor

doi: 10.1021/cb800193n

Thus, the concentration of GSH decreases while that of GSSG increases