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2021 (became Septerna) Origin Story : Septerna is co-founded by Robert Lefkowitz, a Duke University biochemist who won the 2012 Nobel Prize in Chemistry for his work decoding G protein-coupled receptors (GPCRs)

Drink 30 mL of fluids per kilogram of body weight (about 0.5 oz per pound) daily to prevent constipation and reduce nausea

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Studies have shown that semaglutide treatment increases populations of Akkermansia muciniphila, a bacteria associated with healthy metabolic function, while decreasing overall microbial diversity