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These factors result in excessive ROS production, which exceeds the antioxidant defenses and perpetuates or worsens inflammation in the mucosa

This substantial reduction in endogenous Pure Copper peptide production directly correlates with the visible manifestations of skin aging, including decreased elasticity, diminished barrier function, increased transepidermal water loss, and reduced capacity for wound healing and tissue repair

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These challenges have led to the development of more stable analogues, improved delivery systems, and increased interest in smaller peptide fragments that retain bioactivity while minimizing these drawbacks [9]

When patients with metabolic syndrome were given an RS-containing diet, plasma triglyceride levels were significantly reduced (Johnston et al