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Beispiel 10: Pharmakokinetische Profile nach Verabreichung an Cynomolgus-AffenExample 10: Pharmacokinetic Profiles after administration to cynomolgus monkeys Es wurde ein empfindlicher Bioassay, der auf der hohen Affinittsbindung an MCRs basiert, durchgefhrt, um die Plasmaspiegel von Verbindung 1 in Cynomolgus-Affen zu berwachen

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ANGPTL4 interacts with Integrin-1 and activates the mesenchymal signal cascade in diabetic tubules and diabetic endothelial cells (Srivastava et al., 2025a