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These therapeutic effects occur after the medication has entered systemic circulation , not during the absorption phase, which means that the presence or absence of food in the gastrointestinal tract at the time of injection is irrelevant to the drug's pharmacological activity

Eli Lilly, the company that manufactures tirzepatide, advises people on oral contraceptives to use backup methods of birth control for four weeks after starting tirzepatide, or if they increase their dosage

The benefits weight loss, improved glucose control, lower blood pressure and so on generally far outweigh the potential risks for those who qualify [intermountainhealthcare.org]

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