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A phase I safety study in healthy adults confirmed that subcutaneous MOTS-c injections at doses up to 10 mg produced no serious adverse events, with a pharmacokinetic profile supporting once-daily or every-other-day dosing [3]

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These findings positioned DHODH as a third axis of ferroptosis defense, alongside GPX4 and FSP1, particularly in mitochondria-rich or metabolically active cell types

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Glutathione gets to work at a cellular level, targeting the root cause of discoloration

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