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Cerebrolysin has 2 Cochrane reviews and 13 randomized human trials behind it

Regulatory status: Not approved by the FDA (or any regulatory agency) for human use

in this case the allele ADH1B*2, which results in the alcohol dehydrogenase enzyme converting alcohol to toxic acetaldehyde more quickly than other gene variants common outside East Asia

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During ethanol metabolism, alcohol dehydrogenase (ADH) converts ethanol to acetaldehyde in the liver, then aldehyde dehydrogenase (ALDH2) oxidizes acetaldehyde to acetate