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The broader benefits of GLP-1 therapyincluding improvements in body composition, insulin resistance, cardiovascular risk factors, sleep apnea, and overall metabolic healthcan all positively influence reproductive function. Because infertility, obesity, metabolic syndrome, and low testosterone frequently coexist, treating the underlying metabolic disease may have substantial downstream reproductive benefits

(2020a)

xGLP-E4 showed higher activity toward GLP1R than wild-type human GLP-1

Nature 91 SunJ.WangL.BaoH.PremiS.DasU.ChapmanE