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Traditional treatments for AD, such as cholinesterase inhibitors and NMDA receptor antagonists, offer only modest symptomatic relief, while L-DOPA for PD primarily addresses motor symptoms, with limited efficacy against non-motor dysfunctions and progression

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It may achieve this by upregulating vascular endothelial growth factor (VEGF), an endogenous protein responsible for stimulating the growth of new blood vessels [4]

This prevented a rapid decrease and extended the effective exposure period [52,53,54,55]