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Growth hormone therapy and its relationship to insulin resistance
Slowing the climb is the main lever
Simultaneously, central GLP-1 neurons modulate reward processing, mood, and cognitive function
The latest dual-action GLP-1 analogue, tirzepatide , which also affects GIP receptors, was approved in the US in 2022 as the drug Mounjaro for the treatment of type 2 diabetes, and in 2023 as Zepbound for the treatment of obesity and excess weight, as well as obstructive sleep apnea syndrome in obese individuals
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