Any sort of GI problem (including hormone imbalances like thyroid problems) may limit absorption
This is why its of much interest in scientific studies concerning biochemical compounds
Expert opinion Hunt et al 23 Data from randomized controlled trials and observational studies for parenteral treatment are lacking
It is commonly explored for its relationship to NNMT activity, with research interest centered on how that pathway may influence fat metabolism, lean mass support, and energy balance
Research has examined investigated effects on adipocyte differentiation markers, browning markers (the conversion of white adipose toward brown-like phenotype), and broader adipocyte biology
All of this was explained to me when I met two representatives of the MHRA two years ago, (their offices, incidentally are a nightmare for vertigo sufferers like me its all wall to wall glass even the floors)