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For research protocols prioritising maximum therapeutic ceiling and mechanism breadth, our editorial pick is retatrutide

N Engl J Med (2012) 366(17):157785.10.1056/NEJMoa1200111 13 SchauerPRKashyapSRWolskiKBrethauerSAKirwanJPPothierCEet alBariatric surgery versus intensive medical therapy in obese patients with diabetes

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Retatrutide 10mg vial: Add 2mL BAC water for a 5mg/mL concentration

Most GLP-1 medications are taken via injection daily or weekly

Cardenas-Moreno has received consulting or speaker fees from Astrazeneca, Novo Nordisk, Novartis, Sanofi and Boehringer Ingelheim