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Randomized, double-blind, placebo-controlled phase 3 study of bardoxolone methyl in patients with diabetic kidney disease: design and baseline characteristics of AYAME study

This shift not only allows for rapid production of energy but also for maintenance of NADH/NAD + redox ratio, which is required for metabolic processes, such as aerobic glycolysis, the TCA cycle, OXPHOS, FAO, serine biosynthesis and antioxidant defense

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doi: 10.1016/j.bbagen.2012.09.018

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