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Current clinical-trial and FDA materials provide additional topical, compounding, and regulatory context [9] [10] [11] [12]

Separate high-dose oral b12 (1000 to 2000 mcg daily) or regular b12 injections (1000 mcg weekly or monthly) offer more reliable repletion

Always consult the medication manufacturer instructions for dilution requirements and compatibility

How does a substance or method get included on the WADA Prohibited List

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Oxidative stress is associated with induction of neurosteroid biosynthesis in the human brain (284), and TSPO ligands ( N , N -dialkyl-2-phenylindol-3-ylglyoxylamides) that also show anxiolytic activity promote a reduction in oxidative stress and pro-inflammatory enzymes in glial cells via promotion of neurosteroid synthesis (133)