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Common schedules include weekly injections for initial deficiency correction, then bi-weekly or monthly injections for maintenance, or as-needed for energy or performance boosts

At high pharmacological doses (used historically to lower cholesterol), niacin also affects lipid metabolism, as described in a clinical study

Vitamin B12 is essential for energy, a healthy nervous system and the production of red blood cells

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Adipose triglyceride lipase-null mice are resistant to high-fat dietinduced insulin resistance despite reduced energy expenditure and ectopic lipid accumulation

Hirata, F., & Axelrod, J