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In a model of non-ischemic HF in dogs (tachycardiomyopathy induced by pacemakers), IV infusion of GLP-1 increases left ventricular (LV) contractility (LV dP/dt increased by 98%, stroke volume by 102%, and cardiac output by 57%) and decreases LV end-diastolic pressure, heart rate, and systemic vascular resistance

Research shows that artificially activating these receptors inhibits food intake, even when the stomach is empty

It should be stored at room temperature (20C-25C), avoiding moisture and high temperatures.

Higher doses produce more side effects with both drugs