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Cell SignallingSignaling (2014) 26(8):175363

These deposits usually result from excess cholesterol or bilirubin in the bile

Metabolites such as SCFAs, TMAO and LPC are deeply involved in the evolution of resistance to ADT, chemotherapy and immunotherapy through the regulation of AR signaling, drug efflux and immune evasion

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As crucial regulators of local immune responses and tissue repair, macrophages in diabetic wounds show dysregulated switching from M1 to M2, resulting in a poor regenerative environment, exacerbated tissue damage, and delayed wound healing 63

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