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Cellular swelling, karyolysis, karyorrhexis, vacuolization, release of cellular contents, endoplasmic reticulum stress, sterile inflammation, and autophagy are other mechanisms associated with APAP hepatotoxicity

Liraglutide ameliorates cerebral ischemia in mice via antipyroptotic pathways

While oral NAC is an effective alternative, its use is often limited by gastrointestinal intolerance, particularly in patients experiencing nausea or vomiting

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