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One notable difference is that tirzepatide is a dual-agonist (GLP-1 and GIP) while retatrutide is a triple-agonist (GLP-1, GIP, and glucagon)

If you are pregnant or breastfeeding, have a history of certain thyroid cancers or pancreatitis, or have other specific medical conditions, GLP-1 therapy may not be an option, and we will tell you that directly rather than finding a way to prescribe

Kumaravel A, Zelisko A, Schauer P, Lopez R, Kroh M, Stevens T

Food reduces the bioavailability of oral semaglutide by up to 40%

Rather than a reason to panic, this finding should be seen as a reminder: no drug is without risk, but knowledge empowers both patients and providers to act quickly if needed

Water and hydration - with some salt from time to time will help for better hydration