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Ann Intern Med (2003) 139(11):9302.10.7326/0003-4819-139-11-200312020-00012 5 National Institutes of Health

In addition, glutamate and alanine in positions 21 and 24 respectively were reversed, and a glycine residue at position 29 was replaced by asparagine

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essentially the immune systems mistakenly recognises pancreatic beta cells (The cells that release insulin in your body) as a foreign substance/organism, and therefore must be removed/killed from the body

Maintaining regular sleep patterns and gentle physical activity as tolerated may help manage these symptoms