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A modified MSH, covalently coupled to poly-L-glutamic acid (PGA-MSH), showed beneficial effects for endodontic regeneration due to its ability to induce cell adhesion, proliferation and reduction of IL-6 and TNF- on dental pulp fibroblasts

doi: 10.1016/j.indcrop.2022.115603 61 LiangL.LiJ.JinL.YanK.PanY.ShangQ

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Afterwards, excessive ROS would interfere with Ca 2+ homeostasis in cardiomyocytes, affecting multiple ion transporters responsible for myocardial electrical activity and bringing about diastolic and systolic dysfunction and arrhythmia

Some that are already in clinical use are being applied in combination, such as dual inhibition of angiotensin receptors and angiotensin-converting enzyme

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