Glutathione not only has a role in the skins melanin formation, it can also interrupt the enzyme that causes melanin overproduction
Bellia F, Lanza V, Naletova I, Tomasello B, Ciaffaglione V, Greco V, Sciuto S, Amico P, Inturri R, Vaccaro S, Campagna T, Attanasio F, Tabb G, Rizzarelli E (2023) Copper(II) complexes with carnosine conjugates of hyaluronic acids at different dipeptide loading percentages behave as multiple SOD mimics and stimulate Nrf2 translocation and antioxidant response in in vitro inflammatory model
Phase I safety studies report good tolerability with no serious adverse events at tested doses [9]
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NAD+ is designed to support cellular energy and DNA repair, while glutathione is focused on detoxification and protecting cells from oxidative stress
[2] The study was not controlled for cream vehicle application alone without active ingredients