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TB-500 is commonly discussed as a synthetic fragment related to thymosin beta-4 biology, which is involved in actin regulation, cell migration, and wound-healing research

doi: 10.3389/fmed.2021.642710 312 YangC-ABauerSHoY-CSotznyFChangJ-GScheibenbogenC

For more complete reviews of collagen biochemistry and clinical aspects of EDS, the reader is directed to recent reviews (1, 2)

Some patients report mild diarrhoea, nausea, or headache following administration, though these symptoms are usually transient