Epithelial HIF2 expression induces intestinal barrier dysfunction and exacerbation of arthritis

This work was supported by Integrated Chinese and Western Medicine (YC-2023-0404), Fudan Zhangjiang Clinical Medicine Innovation Fund Project (KP0202118), Fudan Good Practice Program of Teaching and Learning (FD2023A227), Project of Key Medical Discipline of Pudong Hospital of Fudan University (Zdxk2020-11), Project of Key Medical Specialty and Treatment Center of Pudong Hospital of Fudan University (Zdzk2020-24), Pudong New Area Clinical Plateau Discipline Project (PWYgy-2021-03), the Natural Science Foundation of China (21675034), National Natural Science Foundation of China (81370932), Shanghai Natural Science Foundation (19ZR1447500), Pudong New Area Clinical Characteristic Discipline Project (PWYts2021-11), Pudong New Area Clinical Characteristic Discipline Project (PWYts2021-01), Pudong Research Project (YC-2023-0202, YC-2023-0607, PWRI2023-08), Wenzhou Medical University Education Grant (JG2021197), Pudong Research Project (PWRl2023-08, YC-2023-0128

For this test, we only used phosphorylation site ratios quantified in all three biological replicates of at least one condition
The metabolic pathways and corresponding enzymes are organized around the TCA cycle at the center, branching out to include amino acid metabolism, purine metabolism, and the glutathione cycle, highlighting the interconnectivity and complex response to the oxidative stress induced by the absence of GR
Arifin WN, Zahiruddin WM
Expiration: MFG date on the bottom of the bottle is Manufacture Date, not expiration