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Peripheral low-grade inflammation exacerbates this effect by diverting tryptophan metabolism (usually a precursor for serotonin) toward the KYN pathway, resulting in reduced peripheral tryptophan availability and lower central serotonin synthesis (24) (Figure 11)

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This review highlights the particular aspects of the stable gastric pentadecapeptide BPC 157 pleiotropic beneficial activity [1,2,3,4,5,6,7,8,9,10,11] and its possible relations with neurotransmitters activity [12,13,14] so far not emphasized

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