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Altered adipokine levels have also been found in depressed individuals, albeit showing some differences related to sex, age, and body mass index [88]

The REIMAGINE trials each met their primary endpoint, demonstrating significant reductions in HbA 1c and met their confirmatory secondary endpoints in reduction of bodyweight

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[58] pyruvate, which is the only source of endogenous lactate in the brain, is at a crossroads of a number of metabolic pathways i.e