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Thermal stability was measured following solubilization in n -dodecyl--d-maltopyranoside supplemented with cholesteryl hemisuccinate (see Methods)

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Those include: Pregnant people , who can pass on a kind of irreversible brain damage to their children, called kernicterus, if they're on berberine Breastfeeding mothers, because berberine can negatively impact child development Anyone who's on other drugs should exercise caution, because berberine can impact a key enzyme which influences the way our body metabolizes many other drugs

The mean age of onset is approximately 34 years, and prevalence increases with increasing age [24]