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The bone marrow sample is examined in a laboratory to look for other causes of anemia and red blood cell abnormalities

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Although the wild-type cells retained the same filamentous form in both culture media, by comparing the metabolic activities between arginine and proline media, 16 metabolic pathways were downregulated, whilst 11 metabolic pathways were upregulated for the wild type compared to the gdh3 / gdh3 mutant