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Wilkinson and Hardman, 2020)

Antioxidant Signaling and ROS Attenuation Studies in aged rodent models demonstrated that Epitalon treatment reduced markers of oxidative stress, including lipid peroxidation products (MDA) and protein carbonylation, while upregulating superoxide dismutase (SOD) and catalase activity

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However, this effect is not dose-dependent, and the highest values were reached with 50 ng/mL on day 3 after IGF-1 administration (Raghavan et al., 2012)