5-Amino-1MQ (5-amino-1-methylquinolinium iodide) is a small-molecule research compound and a selective inhibitor of nicotinamide N-methyltransferase (NNMT)
Cyanocobalamin works well because it easily turns into the active Vitamin B12 in the body
However, if untreated, a vitamin B12 deficiency can lead to serious symptoms, including nerve damage or pernicious anaemia a condition when your body doesnt have enough B12 to make the red blood cells it needs
Rather than directly supplying NAD+ precursors (like NMN or NR), it works by blocking an enzyme that consumes nicotinamide, theoretically preserving the substrate pool for endogenous NAD+ production
This includes vegans and vegetarians, older adults, individuals with atrophic gastritis, pernicious anemia, gastrointestinal disorders, those who have had gastrointestinal surgery and people who take certain medications including, but not limited to, estrogen (HRT), and birth control pills
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