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While some people might feel a slight pinch or discomfort, it is generally well-tolerated

It is recommended that these medications be stored in a cool, dry place away from direct sunlight and moisture

Most common side effects (12mg dose, across TRIUMPH-4 and TRIUMPH-1): Nausea: 43% TRIUMPH-4 / ~38% TRIUMPH-1 (mostly during dose escalation) Diarrhea: 33% / ~28% (peaks weeks 48, improves by week 16) Dysesthesia: 20.9% (tingling sensations onset variable, long-term persistence unknown) Vomiting: 21% / ~25% (decreases after month 3) Constipation: 25% Discontinuation rates: 18.2% in TRIUMPH-4 (osteoarthritis population), 11.3% in TRIUMPH-1 (general obesity population)

rush it and the side effects flare

When the liver breaks down RBCs, it releases bilirubin

However, it is best to avoid prolonged exposure to water or intense heat