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Its functional parts include the recognition arm to selectively bind the target RNA, the catalytic core to employ magnesium ions, and other assisting factors to activate water molecules, which attack and cleave the target phosphodiester bond of the RNA

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Consistent with established principles, CL maturation begins before birth, making PMA more physiologically relevant than postnatal age ( versus age to describe CL maturation (Supplementary Figure S3), suggesting future studies should expand sample sizes to validate these maturation dynamics