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The latter is mostly likely due to a secondary bacterial infection

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Li J, Kataoka K

Administration Vitamin B12 injections are usually administered intramuscularly, often in the upper arm or thigh

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Anastomoses between two defects in the corresponding tissues (i.e., in esophagus and skin (Skorjanec et al., 2009), duodenum and skin (Skorjanec et al., 2015), colon and skin (Sikiric et al., 2020a)