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Despite the efficacy of current antiepileptic drugs, almost 30% of patients with epilepsy are refractory to medical treatment, have progressive cognitive impairment, and require neurosurgical resection of the epileptic tissue to ameliorate recurring seizures (Laxer et al., 2014)

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Briefly, GSH-depleted cells (210 6 cells/ml) treated with ASA with or without NAC were incubated with 5 M DCFDA for 30 minutes at 37C

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