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doi:10.3390/nu14081549
Bariatric and upper gastrointestinal surgery exerts profound improvements in glucose metabolism and can even induce remission of type 2 diabetes (T2D) (1, 2), thus demonstrating the importance of the gastrointestinal tract as a key regulator of systemic glucose metabolism
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3.2 Therapeutic potential in obesity Although the incretin effects of GIPR undoubtedly play a crucial role in preventing postprandial glucose excursion, there is still intensive debate on whether the GIPR should be activated or inhibited for the treatment of obesity
World J Gastroenterol
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