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Poor diet, illness, inactivity, and even aging deplete your glutathione stores

These agents mimic the action of naturally occurring GLP-1, an incretin hormone produced by intestinal L-cells in response to food intake

This area is generally meatier and further away from major nerves and bones

Given the similarity in structure between carnitine and choline, they figured that the same kind of transformation would occur into TMAO

With 1 mg = 1,000 mcg, start low and adjust based on tolerance to minimize side effects

In 2021, the FDA approved another, higher-dose injectable version for weight management in adults Novo Nordisk brought this to market under the brand name Wegovy