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FIGURE 3 The basic state of CPT1A is a trimer, which has the potential to further merge into a hexamer, and may play a role in the sensitivity to malonyl-CoA (Faye et al., 2007)

It is worth to mention that available reports describing the encapsulation of GSH- or albumin-protected AuNCs are limited to hydrophilic, rather than hydrophobic, matrices such as nanogels 25 , aqueous core of microcapsules 26 , silica nanoparticles, protein nanoparticles 27,28 , polymer nanoparticles 29,30 and metal-organic frameworks 31

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There are likely to be other homeostatic mechanisms that also play a role in limiting weight loss with SGLT2 inhibitors

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