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It was engineered to isolate metabolic signaling associated with lipid and glucose regulation while excluding the growth-promoting effects of full-length HGH

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For background on the broader angiotensin IV / AT4 system the work was built on, see Wright and Harding 1995 (PMID 7768321) and Wright et al

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doi:10.3390/ijms16047210 76

[Abstract]2023 Jun 6;42(1):142