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When the bi-directional connection between the brain and the gut (also called the gut-brain axis) is underdeveloped, and/or the ecosystem becomes imbalanced, I often see ADHD paralysis
We monitor PubMed for new peer-reviewed studies on this topic and email a short summary when something meaningful changes.
So I think that what were missing in the whole discussion is thinking about how do we ramp up mitochondrial energy production, how do we prevent it from declining and aging so that the body, so that the brain can rightly perceive that I am in a state of abundance
However, once diagnosed it presents a difficult management problem in patients suffering from pernicious anemia, as there is no substitute
What every patient with PA would like (and deserves) is a quality of life that allows them to stay awake at work, not have peripheral neuropathy, not have brain fog, anxiety or any of the countless other symptoms that plague people who are unable to absorb B12 due to lack of intrinsic factor