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10.1016/j.heliyon.2024.e29654 83 WeichhartT

B., & Klein, K

MC1R Binding and Eumelanin Signalling MT-1 exerts its primary pharmacological action by binding to the melanocortin 1 receptor (MC1R) on melanocytes in the skin

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Summary MOTS-c represents one of the most exciting mitochondrial discoveries of the past decade a naturally encoded peptide that acts as both a metabolic regulator and a cellular stress signal

If particulates remain after a second attempt, the peptide was likely damaged during manufacturing or shippingtemperature excursions above 20C during transport can cause partial denaturation that manifests as incomplete dissolution