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Lasting results come from medically sound treatment, not from white knuckling through another diet

GLP-1 agonists are not appropriate for everyone who wants to lose weight

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In db/db mouse models of advanced diabetes characterized by uncontrolled hyperglycemia and catabolic weight loss, PG-102 achieved superior and sustained glycemic control compared with semaglutide or tirzepatide while preserving body weight, uncoupling glycemic control from catabolic weight loss

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Most medications are safe to add, but watching for compounding GI symptoms or hypoglycemia risk is part of routine care