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specific tissues or organs) are unable to produce enough glutathione to protect themselves against normal levels of toxins and free radicals or your body starts producing more free radicals than normal levels
Oxidative stress induces the dissociation of the NRF2-Keap1 complex When cells undergo oxidative stress, ionizing radiation, or chemical stimulation, it may lead to the generation of reactive oxygen species (ROS) or reactive oxygen free radicals within the cells, triggering an oxidative stress response
Acknowledgment The financial support of Babol University of Medical Sciences is appreciated
DOI: 10.1186/s12950-019-0218-y [Google Scholar] Chen J, Xie JJ, Shi KS, Gu YT, Wu CC, Xuan J, et al
While IL-1 was only trending, IL-18 was significantly elevated in comparison to vehicle-treated cells (Fig
