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In clinical trials, patients using Mounjaro have experienced a 5% to 15% reduction in body weight over 6 months, although individual results can vary

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The tryptophan-kynurenine pathway functions as a stress-activated metabolic system that diverts tryptophan from serotonin synthesis toward kynurenic acid production, which acts as a glutamate receptor antagonist and may contribute to anxiety pathophysiology through altered glutamatergic neurotransmission (Butler et al., 2022)

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