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Considering c-MET in aspects of cell signaling network through cross-talking with EGFR, VEGFR-2 and other signaling molecules, it is necessary to develop antibodies that are able to inhibit simultaneously two signaling cascades to achieve maximal therapeutic activity [77, 119]

The cFSP1 N lacks only the myristoylation motif, and almost resembles full-length cFSP1 in structure

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