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In adverse event reports, alogliptin was associated with 3 cases of biliary malignancies, linagliptin with 9 cases, and their 95%CI for ROR and EBGM05 exceeded the signal detection thresholds, indicating a possible statistically significant correlation

Risk-Benefit Assessment : The potential benefits must be carefully weighed against known and unknown risks, particularly given the limited long-term safety data in adolescents

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Grber U, et al

Theoretically, the combination of retatrutide with a ketogenic diet could produce even more robust ketosis than either intervention alone, though clinical data on this specific combination is not yet available

Her mission is to teach her patients how to have a high level of success in keeping the weight off after their program ends