With respect to insulin responses and metabolism, activation of AKT2 (PKB) and PKC- lead to translocation of GLUT4 containing vesicles to the plasma membrane in adipocytes and skeletal muscle cells resulting in increased glucose uptake in these two tissues
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Effect of MELANOTAN, [Nle4, D-Phe7]-alpha-MSH, on melanin synthesis in humans with MC1R variant alleles Peptides, 2006, melaninrespons vid MC1R-varianter PMID 12591111 Ter Laak MP et al